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<body lang=TR link=blue vlink="#954F72" style='word-wrap:break-word'>

<div class=WordSection1>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>ORIGINAL RESEARCH�
�</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Cosar et al</span></p>

<p class=MsoNormal align=center style='text-align:center'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Classifying
Invasive Lobular Carcinoma as Special Type Breast Cancer May Be Reducing Its
Treatment Success: A comparison of Survival Among Invasive Lobular Carcinoma</span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Rusen Cosar<sup>1</sup>,
Necdet Sut<sup>2 </sup>, Sernaz Topaloglu<sup>3 </sup>, Ebru Tastekin<sup>4 </sup>,
Dilek Nurlu<sup>1 </sup>, Talar Ozler<sup>1 </sup>, Eyl�l �en�deyici<sup>5 </sup>,
Melisa Dedeli<sup>1 </sup>, Mert Chousein<sup>1</sup>, Irfan Cicin<sup>3</sup></span></p>

<p class=MsoNormal style='text-align:justify'><sup><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>1</span></sup><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Trakya
University Faculty of Medicine Department of Radiation Oncology, Edirne, Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><sup><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>2</span></sup><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'> Trakya
University Faculty of Medicine Department of Biostatistics, Edirne, Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><sup><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>3</span></sup><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Trakya
University Faculty of Medicine Department of Medical Oncology, Edirne, Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><sup><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>4</span></sup><a
name="_Hlk106560946"><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Trakya
University Faculty of Medicine </span></a><span lang=EN-US style='line-height:
200%;font-family:"Times New Roman",serif'>Department of Pathology, Edirne,
Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><sup><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>5</span></sup><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Trakya
University Faculty of Medicine, Edirne, Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Correspondence: Ru�en
Co�ar</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Trakya University
School of Medicine, </span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Department of
Radiation Oncology, Edirne, Turkey</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Tel: +902842361074</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Email: </span><span
lang=EN-US><a href="mailto:rusencosar@trakya.edu.tr"><span style='line-height:
200%;font-family:"Times New Roman",serif'>rusencosar@trakya.edu.tr</span></a></span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Disclosure</span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>The authors have
declared that no competing interests exist. The authors alone are responsible
for the content and writing of the paper. The authors declared that this study
has received no financial support. �The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the
manuscript.� Voluntary consent form was given to patients or official guardians
of deceased patients to use file information. File information was used after
the forms were signed by the patient or official guardians of deceased
patients.</span></p>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Abstract: </span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Purpose: </span><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif;
font-weight:normal'>The literature contains differentiating information
regarding the prognosis of invasive lobular carcinoma. We aimed to address the
inconsistency by comparatively examining the clinical features and prognosis of
invasive lobular carcinoma patients in our university and to report our
experience by dividing our patients into various subgroups.</span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Patients and methods: </span><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif;
font-weight:normal'>Records of patients with breast cancer admitted to Trakya
University School of Medicine Department of Oncology between July 1999 and December
2021 were reviewed. The patients were divided into three groups (No-Special
Type Breast Cancer, Invasive Lobular Special Type BC, No-Lobular Special BC).
Patient characteristics, treatment methods and oncological results are
presented. Survival curves were generated using the Kaplan�Meier method.
Statistical significance of survival among the selected variables was compared
by using the log-rank test.</span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Results: </span><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif;
font-weight:normal'>The patients in our study consisted of 2142 female and 15
male breast cancer patients. There were 1814 patients with Non-Special Type
Breast Carcinoma, 193 patients with Lobular Special Type Breast Carcinoma, and
150 patients with Non-Lobular Special Type Breast Carcinoma. The duration of
disease free survival (DFS) was 226.5 months for the No-Special Type group,
216.7 months for the No-Lobular Special Type group, and 197.2 months for the
Lobular Special Type group, whereas the duration of overall survival (OS) was
233.2 months for the Non-Special Type group, 227.9 for the No-Lobular Special
Type group, and 209.8 for the Lobular Special Type group. The duration of both
DFS and OS was the lowest in the Lobular Special Type group. Multivariate
factors that were significant risk factors for OS were Lobular Special Type
histopathology (p=.045), T stage, N stage, stage, skin infiltration, positive
surgical margins, high histological grade and mitotic index. Modified radical
mastectomy, chemotherapy, radiotherapy and use of Tamoxifen and aromatase
inhibitors for more than 5 years were significant protective factors for
overall survival.</span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Conclusion: </span><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif;
font-weight:normal'>The histopathological subgroup with the worst prognosis in
our study was Lobular Special Type. Duration of DFS and OS were significantly
shorter in Lobular Special Type than No-Lobular Special Type group. Whether
Lobular Special Type should be classified as a Special Type Breast Tumor should
be reconsidered, and a more accurate treatment and follow-up process may be
required.</span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Keywords: </span><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif;
font-weight:normal'>No-Special Type Breast Cancer, Special Type Breast Cancer,
Invasive Lobular Cancer, Non-Lobular Special Type Breast Cancer, Invasive
Ductal Breast Cancer</span></h1>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Introduction</span></h1>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Invasive lobular
breast cancer (ILC) is the most common special histological type of breast
cancer (BC). While ILC accounts for 5% of invasive carcinomas, its incidence
has increased up to 10-14% with the developments in diagnostic methods and
novel discoveries. However, ILC remains less common in Asian populations (2�6%)<sup>1-6</sup>.
As the incidence of ILC is significantly less than invasive ductal carcinoma
(IDC), the most common histopathological subtype of breast cancer, its clinical
and prognostic features and biological behavior become clearer as more studies
are published<sup>7-15</sup>. </span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>ILC is within the
Special Type BC group, along with tubular, mucinous, papillary, micropapillary,
medullary, metaplastic, and apocrine histopathological subtypes, whereas IDC is
among the No-Special Type BC group composed of highly heterogeneous subtypes<sup>10</sup>.
ILC stands out among the other histopathological subtypes in the Special Type
BC group with its distinct clinical course, prognosis and biological features.
While the survival rate of ILC was better than or similar to that of IDC in
series with less than 6 years of follow-up, the prognosis of ILC was found to
be worse than IDC in series with longer follow-up. However, the St Gallen
International Expert Consensus guidelines and the National Comprehensive Cancer
Network (NCCN) recommend that ILC should be treated with the same treatment
paradigms as IDC, despite their many different features. Therefore, systemic
treatment decisions for ILC and IDC are often similar (10). Highlighting ILC as
the subgroup with better prognosis in the series published in the past years
may have prevented the treatment decision from being more aggressive, resulting
in worse survival than IDC in the long term<sup>6-9, 11-14</sup>.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Treating the
�Special� ILC similarly to the �No-Special� IDC may cause the clinicians to
overlook important details regarding this patient group<sup>13</sup>. However,
larger tumor diameter, more lymph node metastases, high hormone receptor
positivity, loss of E-cadherin and the potential of atypical metastasis are
among the currently known distinct features of ILC<sup>3, 4</sup>. Unlike IDC,
ILC shows different growth patterns and biological features, rather than masses
that can easily be diagnosed with palpation or mammography. Additionally, an
increased rate of multiple metastases, low rates of pathological complete
response to neoadjuvant chemotherapy, and frequent positive surgical margins
are among the features that make ILC more remarkable<sup>14,15</sup>.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Different
information in the literature regarding prognosis has led us to comparatively
examine the clinical features and prognosis of ILC patients in our series. We
aimed to determine our own patient characteristics and report our treatment
experience of ILC by dividing our patient series into various subgroups.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Material and methods</span></h1>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Patient</span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'> <b>characteristics</b></span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Patients with
breast cancer who applied to Trakya University School of Medicine Departments
of Radiation Oncology and Medical Oncology between July 1999 and December 2021
were retrospectively analyzed. Approval was obtained from the Human Research
Ethics Committee of Trakya University Medical Faculty Hospital (TUTF-BAEK
2022/170) for the use of patient information in the study. The consent form was
submitted to the local ethics committee (Trakya University Faculty of Medicine
Dean's Non-Invasive Scientific Research Ethics Committee, Edirne, Turkey).
Informed consent forms were prepared in accordance with the Declaration of
Helsinki. In the study, permission was obtained from the patients, and if the
patient died, from the legal guardians of the patients, by signing a written
consent form, to use the information in the registry files containing the
patient information.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Medical
records and pathological reports were retrospectively converted into SPSS data
to evaluate the clinicopathological features. After excluding 190 patients with
ductal carcinoma in situ and lobular carcinoma in situ from a total of 2347
breast cancer patients, the remaining 2157 patients with invasive carcinoma
were included in the study. <a name="_Hlk107681669">The patients in our series
consisted of 2142 female and 15 male breast cancer patients.</a> No-Special
Type BC (Completely invasive ductal carcinoma, IDC) and Special Type BC were
divided as invasive lobular carcinoma (ILC), mixed type (IDC+ILC), epidermoid
carcinoma, mucinous carcinoma, medullary carcinoma, papillary carcinoma,
tubular carcinoma, adenoid cystic carcinoma, secretory carcinoma, apocrine
carcinoma, and metaplastic carcinoma. Later, the patients were divided into
three groups: <a name="_Hlk107681708">Non-Special Type BC (IDC) (n=1814),
Lobular Special Type (ILC, ILC+IDC mixed type) (n=193), and Non-Lobular Special
Type BC (n=150). </a>Disease-free survival (DFS) and overall survival (OS)
analyzes of the patient groups were performed. Patient characteristics were
tabulated as ratios and numbers, and comparisons were made between groups.
Finally, univariate and multivariate analyzes of factors affecting DFS and OS were
performed. </span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Clinicopathological
Features</span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Pathological and
clinical staging in our series was performed according to the seventh edition
of the American Joint Committee on Cancer Staging Manual<sup>16</sup>. IDC,
Non-Lobular Special Type, ILC, and histopathological diagnoses were evaluated
using hematoxylin-eosin staining by pathologists specializing in breast cancer
at Trakya University School of Medicine Department of Pathology. Estrogen
receptor (ER) and progesterone receptor (PR) positivity were determined by
immunohistochemical staining. Hormone receptor positivity was defined as an ER
score greater than or equal to 3 on the Allred Score (17). HER2 positive was
defined as a Herceptest score of 3+ or a Herceptest score of 2+ followed by
fluorescent in situ hybridization (FISH) positive<sup>18</sup>. Luminal type
was defined as ER positive and HER2 negative. Histological grading was done
using the Nottingham histological grading system. Pathological staging for
extensive intraductal carcinoma (EIC), lymphovascular invasion (LVI), and
perineural invasion (PNI) was done according to the seventh edition of the
American Joint Committee on Cancer Staging Manual<sup>17</sup>. </span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Statistical
Analysis</span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Numerical results
are expressed as the mean � standard deviation, and categorical results are
shown as n (%). Kaplan-Meier method was used to generate the survival curves.
Log-rank test was used to compare the statistical significance of survival
among the selected variables. Hazard ratios were estimated using univariate Cox
regression analysis. Multivariate Cox regression analysis with backward
elimination method was used to estimate hazard ratios and identify independent
prognostic factors. All p values are two-sided, and <i>p&lt;0.05</i> indicates
statistical significance. Data analysis was performed using SPSS version 20.0
(IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corp.).</span></p>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Results</span></h1>

<p class=MsoNormal style='text-align:justify;text-autospace:none'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Out of
2157 patients, 1814 patients had No-Special Type BC and 342 patients had
Special Type BC. No statistically significant difference between DFS and OS was
found (Table 1, Figure 1a, 1b).</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>In the
second step, we divided our patient series into three groups as No-Special Type
BC (n=1814), ILC Special Type BC(n=193), No-Lobular Special Type BC (n=150).
The rate of ILC patients in our series was 8.9%. 4.1% (n=8) of ILCs contained
pleomorphic components.� When all three groups were compared, the differences
between the durations of both DFS and OS were statistically significant. The
duration of DFS was 226.5 months for the IDC group, 216.7 months for the
No-Lobular Special Type group, and 197.2 months for the ILC group, whereas the
duration of OS was 233.2 months for the IDC group, 227.9 for the No-Lobular
Special Type group, and 209.8 for the ILC group. The duration of both DFS and
OS was the lowest in the ILC group (Tables 2, Figure 2a, 2b). </span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>The
histopathological subgroup distribution, which consisted of ER, PR, Ki67 and
CerbB2, was 80.98% Luminal AB, 11.41% Triple Negative, 7.1% HER2 enriched for
IDC, while Non-Lobular Special Type was divided as 68.67% Luminal AB, 24.67%
Triple negative, 6.67% HER2 enriched, and ILC was divided as 94.30% Luminal AB,
4.66% Triple negative, 1.04% HER2 enriched. The subgroup dominating the
histopathological subgroup of ILC was Luminal A-B with a rate of 94.30% (Fig.
3a, 3b, 3c).</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Patient
characteristics of all three groups (IDC, Non-Lobular Special Type, ILC) were
analyzed (Table 3). Gender, age, menstruation, family history, histological
type, tumor quadrant, T stage, N stage, stage, metastasis site, breast surgery
type (modified radical mastectomy/</span><span lang=EN-US> </span><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>breast
conserving surgery), axillary surgery type (axillary curettage</span><span
lang=EN-US>/</span><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>sentinel
lymph node sampling), skin infiltration, surgical margin ( in patients with
positive surgical resection margin, re-excision was performed first and the
surgical resection margin was positive despite this), tumour grade, mitotic
index (MI), ER, PR, Ki67 (&lt;15, &#8805;15), HER2, EIC, LVI, PNI, subgroup
(Luminal A, Luminal B, Triple Negative, HER2 enriched), presence of
anti-hormonal therapy, duration of Tamoxifen (TAM) and Aromatase Inhibitor (AI)
use, use of Herceptin, and type of chemotherapy (CT) [ No CT, AC+TXT
(doxorubicin and cyclophosphamide followed by paclitaxel), FAC (fluorouracil,
doxorubicin, cyclophosphamide)-FEC (floro-urasil, epirubisin,</span><span
lang=EN-US> </span><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>cyclophosphamide),
-TAC (docetaxel, doxorubicin, cyclophosphamide), FAC-FEC+TXT,</span><span
lang=EN-US> </span><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Ribociclib
+ Palbociclib, CMF (Cyclophosphamide Methotrexate Fluorouracil)] were analyzed
as numbers and rates. Fisher exact test was used to compare the patient characteristics
of the three groups. In the same table was made for the statistically
significant patient characteristics of the three groups (Table 3). </span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>The
distribution of patient characteristics of the 3 histopathological subgroups
are shown in Table 3. Of the 193 patients in the Lobular Special Type BC group
in our series, 138 were pure ILC, and 55 were IDC+ILC BC patients. All patients
in the ILC group were women, mostly over 50 years of age and in the
postmenopausal period. There was no significant difference in the presence of
family history and bilateral arrangement among the 3 groups.</span><span
lang=EN-US> </span><a name="_Hlk125068076"><span lang=EN-US style='line-height:
200%;font-family:"Times New Roman",serif'>While the rate of MRM in breast
surgery was 45.5% (n=982), only 7 of the patients had skin-sparing mastectomy. Periareolar
and multifocal localizations were slightly more common in the ILC group. A
pairwise comparison of patient characteristics of all three groups were done. </span></a></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><a name="_Hlk125068027"><b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>ILC/IDC
patient </span></b></a><a name="_Hlk107520705"><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>characteristics </span></b></a></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>T stage, PNI
positivity, ER and PR positivity rates were higher in ILC, while Ki67, CerbB2
positivity, MI (mitotic index) and histological grade rates were higher in IDC.
Subgroup, rate of anti-hormonal treatment use, duration of TAM and AI use, CT
type, and metastasis location were the features that showed significant
difference between ILC and IDC. �Breast and axillary surgery type and surgical
margin positivity were not different between the two histopathological groups (Table
3). Although not statistically significant, MRM was detected in 47.9% of the
IDC and 51.6% of the ILC.�� While 83.2% of breast cancer patients with IDC
histopathology received chemotherapy, this rate was 78.2% in the ILC
histopathological subgroup, and this difference was calculated differently at
the level of statistical significance.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>ILC/No-Lobular
Special Type <a name="_Hlk107520720">patient characteristics</a></span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>N stage, stage,
surgery type (breast and axillary surgery type), PNI, LVI, subgroup, ER and PR
positivity, HG, duration of anti-hormonal therapy, duration of TAM and AI use,
RT type, CT type, recurrence/metastasis rates and mortality rate were
significantly higher in the ILC group (Table 3). While the MRM rate was 51.6%
more preferred in ILC in surgical treatment, BCS was preferred with 66.2% in
No-Lobular Special Type BC, and this difference was statistically significant.
In No-Lobular Special Type BC, the rate of administration of chemotherapy was
71.3%, the histopathological subgroup in which the least chemotherapy was
preferred.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>IDC/ No-Lobular
Special Type patient characteristics</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>The quadrant where
the tumor is located, T stage, N stage, stage, surgical type (breast and
axillar surgery), PNI, LVI, EIC, subgroup, ER and PR positivity, Ki67 rate,
CerbB2 positivity, HG, presence of anti-hormonal therapy, RT type, CT type,
metastasis location, recurrence/metastasis rate and death rate were found to be
significantly higher in the IDC group. While MRM was preferred 47.9% in IDC
histopathology, 33.8% preferred in No-Lobular Special Type BC histopathology.
In the axillary surgery option, 25% in SLND, IDC, 30.4% in No-Lobular Special
Type BC, and 75% and 69.6% in AK, respectively (Table 3).</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Cox
regression test was used to examine the histopathological subgroups and patient
characteristics with these three different clinical and pathological features.
Multivariate factors that were significant risk factors for DFS in our study
were age, being in the postmenopausal period, multicentric location, T stage,
stage, HER2 positivity and MI, while duration of TAM and AI use, and use of
Herceptin were the significant protective factors for DFS (Tables 4, 5). <a
name="_Hlk107681830">Multivariate factors that were significant risk factors
for OS were ILC histopathology (p=.045), T stage, N stage, stage, skin
infiltration, positive surgical margins, high histological grade and mitotic
index. Modified radical mastectomy (MRM), chemotherapy (CT), radiotherapy (RT)
and use of TAM and AI for more than 5 years were significant protective factors
for OS </a>(Tables 6, 7)</span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Discussion</span></b></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>The classification
of special types of breast cancer recommended by the World Health Organization
is beginning to take a wider place in literature because of their distinct
biological behavior and clinical characteristics compared to no-special types of
breast cancer<sup>15</sup>. Additionally, subtypes in the special breast cancer
group may behave very differently from each other. ILC is considered notable
for its distinctive biological behavior and unusual organ metastases and is
included in Special Type BC because of studies showing it has a better
prognosis than IDC<sup>6, 20-24</sup>. However, studies with longer periods of
follow-up show that ILC has worse prognosis than IDC<sup>6, 14, 25</sup>.
Survival data, which differ from each other and change over the years, call
into question the status of ILC in the Special Type BC group. A separate
classification may be necessary for subtypes in this group.</span><span
lang=EN-US> </span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>When
the patients in our study were divided into two subgroups (No-Special Type BC,
Special Type BC), no significant difference was observed regarding DFS and OS.
When the data was later reanalyzed by removing ILC from the Special Type BC and
treating it as a third, distinct subgroup, ILC was found to have the lowest
duration of DFS and OS. There was a significant difference between the duration
of DFS and OS of IDC and No-Lobular Special Type BC. The duration of DFS and OS
showed significant difference in ILC and No-Lobular Special Type BC as well. Although
IDC and ILC did not have a statistically significant difference regarding DFS
and OS, the difference was still remarkable. ILC and IDC have similar durations
of DFS in the first 6 years. After 6 years however, the survival curve for ILC
was lower than of IDC, and the difference becomes more pronounced after the 17<sup>th</sup>
year. OS for ILC showed a lower course than IDC after 14 years. Although the
difference between the duration of OS in ILC and IDC were not statistically
significant, ILC significantly increased the risk of death by
1.457(1.009-2.104) times, (p=.045) in the Cox regression risk analysis.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Special
Type-BC has a lower incidence, which may have resulted in limited knowledge of
the clinical and biological features of the histopathological subtypes within
the group. However, recent studies with longer follow-up periods have reported
a lower survival rate, especially for ILC, contrary to current information<sup>14,
26</sup>. The increase of incidence and low survival rates may force the
clinicians to reconsider treatment options and the frequency of follow-ups.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>A study
by Toikkanen et al<sup>7</sup> showed ILC had better prognosis than IDC despite
30 years of follow-up, which precludes interpretation by the length of
follow-up alone. As a result, when ILC is analyzed yearly, an increase in its
incidence is seen. Earlier studies<sup>1, 2, 4, 7</sup> show ILC to have lower
grade, mitotic activity, T stage, N stage, stage, and ER positivity with a
higher rate of bilateral arrangement, while more recent studies<sup>14, 26</sup>
report higher histologic grade and mitotic activity, and diagnosis at more
advanced stages. Our study shows that ILC is associated with larger tumor size,
older age, more advanced T and N stage, lower grade, higher ER and PR
positivity, and lower HER2 expression, while the rate of bilateral arrangement
was not higher. This may suggest that the biological behavior of ILC has become
more aggressive over the years. <a name="_Hlk125226603">It should be noted that
the lack of difference between IDC and ILC in terms of surgical margin
positivity, breast surgery and axillary surgery type in our series is evidence
that it does not show a worse prognosis due to residual disease or incomplete
treatment. In the multivariate analysis for DFS, neither breast nor axillary
surgery type increased the risk of events.</a></span><span lang=EN-US> </span><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>In OS,
the risk increased 1.5 times at the statistical significance level (p=0.008) in
patients who underwent MRM. In the axillary surgery type, the risk increased by
1.4 in patients who underwent AC which was close to statistical significance
(p=0.099). In this case, it is proof that more radical surgical interventions
are preferred in patients with high risk. This proves that incomplete surgery
or less aggressive surgical methods are not preferred when interpreting the
results in our series with peace of mind.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Recent
studies suggest whether IDC is the most common histopathological subgroup with
the worst prognosis should be re-evaluated. Having the lowest course on the
survival curve, patients with ILC may require a more careful approach. Our
study suggests that reviewing the current treatment guidelines may be required.
Increased incidence of ILC may be linked to improved diagnostic approach.
Whether ILC has a better or similar prognosis and higher rates of bilateral
arrangement in comparison to IDC deserves restatement. </span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>In
fact, when studies are handled individually and carefully, we can see clues
that may belong to a poor prognosis. For example, studies in which pathological
complete response to neoadjuvant chemotherapy is rare and positive surgical
margin rate is higher in ILC.<sup>13, 22,26 </sup>��This uncertainty has even
made mastectomy a more common treatment option for ILC than IDC<sup>6,7,14</sup>.
Again in a retrospective series, with only larger tumor size as a poor
prognostic factor, ILC had lower survival compared to IDC<sup>6</sup>. Pestalozzi
et al., on the other hand, associated the difference in survival with stage and
reported that the early-stage prognosis of ILC is better than IDC, but the
late-stage prognosis of ILC is worse<sup>14,25</sup>. Since ILC presents itself
with diffuse or spreading lesions rather than a mass, it has been stated that
breast MRI is more helpful than mammography in the diagnosis of such lesions being
satisfied with mammography alone may cause delays in the diagnosis of ILC.<sup>26,27</sup>.</span><span
lang=EN-US style='font-family:"Times New Roman",serif'> Failure to encode the
E-Cadherin protein encoded by the CHD1 gene due to somatic mutation is a
pathognomonic condition for ILC compared to IDC. The E-Cadherin protein not
only plays a role in the adhesion of cells to each other to form tissues and in
the transmission of chemical signals within the cell, cell maturation and
controlling cell movement, it also functions as a tumor suppressor protein<sup>28-30</sup>.
</span><a name="_Hlk124809201"><span lang=EN-US style='line-height:200%;
font-family:"Times New Roman",serif'>Deletion of E-Cadherin and PI3K pathways</span></a><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'> may be
the cause of infiltrative growth pattern and frequent surgical margin positivity<sup>31,32</sup>.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Precisely
for this reason, the results of the ROSALINE (NCT04551495) phase II study with
entrectinib, a tyrosine kinase inhibitor targeting TRK, ROS1 and ALK tyrosine
kinases, with promising in vivo results are eagerly awaited. It is aimed to
measure the antitumor efficacy of entrectinib and endocrine therapy as
neoadjuvant in ER-positive, HER2-negative ILC BC patients<sup>33</sup>. Metastatik
ILC'si olan hastalar i�in, CDH1, NF1, PIK3CA ve TBX3'teki mutasyonlar, t�m�r
mutasyon y�k� (TMB) olarak �l��l�r ve� metastatik IDC'si olan hastalara g�re
daha y�ksektir. The effect of atezolizumab, a carboplatin and immune checkpoint
inhibitors (ICIs), will be measured in the GELATO study, which is planned for
metastatic lobular breast cancer assessing efficacy with mutationa burden (TMB)<sup>34</sup>.</span></p>

<p class=MsoNormal style='text-align:justify;text-indent:36.0pt'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>The
limitation of our study is that, apart from a retrospective series and
comparison of clinical features and treatment outcomes for ILC, no additional
molecular comparison could be made. However, pre-clinical and clinical
molecular studies have been and continue to be conducted in order to explain
the clinical process difference in ILC. The fact that the reason for the
different clinical course and biology of the ILC subtype of breast cancer has
begun to be revealed raises our hopes that the treatment options will also
differ in the coming years and that the risk of developing late recurrence and
metastasis will be reduced or eliminated with more effective treatments.�� </span></p>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Conclusion</span></h1>

<p class=MsoNormal><span lang=EN-US style='font-family:"Times New Roman",serif'>The
increase in the incidence of the ILC histopathological subgroup of breast
cancer in recent years has not only made it possible to understand that it has
a different course compared to IDC, but also has led to the fact that systemic
and local treatment decisions are different over time. In our study and other
studies with long follow-up, we show that ILC has the lowest DFS and OS among
all histological subgroups. Therefore, the classification of ILC into Special
Type BC should be reassessed and current treatment guidelines may need to be
revised, particularly as ILC-specific study results begin to emerge.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<h1 style='text-align:justify'><span lang=EN-US style='font-size:10.0pt;
line-height:200%;font-family:"Times New Roman",serif'>Acknowledgments </span></h1>

<h1 style='text-align:justify'><a name="_Hlk115700902"><span lang=EN-US
style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>Disclosure</span></a></h1>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>The authors report
no conflicts of interest. The authors alone are responsible for the content and
writing of the paper. The authors declare that this study has received no
financial support. Informed consent form was obtained from the patients, their
legal guardians or relatives of the deceased patients to use relevant
information. Any data was used after informed consent forms were signed by the
patients, their legal guardians or relatives of the deceased patients.</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>References </span></p>

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line-height:200%'><span lang=EN-US style='font-size:10.0pt;line-height:200%;
font-family:"Times New Roman",serif'>30.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;
</span></span><span lang=EN-US style='font-size:10.0pt;line-height:200%;
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font-family:"Times New Roman",serif'>32.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;
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<p class=MsoListParagraphCxSpLast style='text-align:justify;text-indent:-18.0pt;
line-height:200%'><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>34.<span
style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp; </span></span><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>AssessinG
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<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='text-align:justify;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>Table
1.</span></b><span lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>
DFS and OS times, comparative Log-rank test, p-value values of Non-Special Type
BC and Special Type BC subgroups obtained using Kaplan-Meier method</span></p>

<p class=MsoListParagraphCxSpFirst style='text-align:justify;line-height:150%'><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify'><span
lang=EN-US style='line-height:107%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:150%'><span
lang=EN-US style='font-size:10.0pt;line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpLast style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<table class=DzTablo41 border=0 cellspacing=0 cellpadding=0 align=left
 width=582 style='width:436.3pt;border-collapse:collapse;margin-left:4.8pt;
 margin-right:4.8pt'>
 <tr style='height:26.0pt'>
  <td width=63 rowspan=2 style='width:46.95pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'><a name="_Hlk112151071"></a></td>
  <td width=86 rowspan=2 style='width:64.45pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
  <td width=168 rowspan=2 style='width:126.2pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Special Type BC</span></b></p>
  </td>
  <td width=132 rowspan=2 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Special Type BC</span></b></p>
  </td>
  <td width=132 style='width:99.35pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><i><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>P</span></i></b><b><span lang=EN-US style='font-size:11.0pt;
  line-height:115%;font-family:"Times New Roman",serif;color:black'> value</span></b></p>
  </td>
 </tr>
 <tr style='height:27.3pt'>
  <td width=132 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Long-rank test)</span></b></p>
  </td>
 </tr>
 <tr style='height:26.0pt'>
  <td width=63 rowspan=3 style='width:46.95pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>DFS</span></b></p>
  </td>
  <td width=86 style='width:64.45pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mean� SD</span></p>
  </td>
  <td width=168 style='width:126.2pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>226,5 � 3,4</span></p>
  </td>
  <td width=132 style='width:99.35pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>208,2 � 6,6</span></p>
  </td>
  <td width=132 rowspan=3 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.234</span></p>
  </td>
 </tr>
 <tr style='height:26.0pt'>
  <td width=86 style='width:64.45pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
  <td width=168 style='width:126.2pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
  <td width=132 style='width:99.35pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
 </tr>
 <tr style='height:27.3pt'>
  <td width=86 style='width:64.45pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal style='line-height:115%'><span lang=EN-US
  style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>95% CI</span></p>
  </td>
  <td width=168 style='width:126.2pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>219,8-233,1</span></p>
  </td>
  <td width=132 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>195,2- 221,2</span></p>
  </td>
 </tr>
 <tr style='height:26.0pt'>
  <td width=63 rowspan=3 style='width:46.95pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>OS</span></b></p>
  </td>
  <td width=86 style='width:64.45pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mean� SD</span></p>
  </td>
  <td width=168 style='width:126.2pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>233,2 � 3,5</span></p>
  </td>
  <td width=132 style='width:99.35pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>221,8 � 6,4</span></p>
  </td>
  <td width=132 rowspan=2 style='width:99.35pt;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.379</span></p>
  </td>
 </tr>
 <tr style='height:26.0pt'>
  <td width=86 style='width:64.45pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
  <td width=168 style='width:126.2pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
  <td width=132 style='width:99.35pt;padding:0cm 5.4pt 0cm 5.4pt;height:26.0pt'></td>
 </tr>
 <tr style='height:27.3pt'>
  <td width=86 style='width:64.45pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>95% CI</span></p>
  </td>
  <td width=168 style='width:126.2pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>226,3 � 240,1</span></p>
  </td>
  <td width=132 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='font-size:11.0pt;line-height:115%;font-family:"Times New Roman",serif;
  color:black'>209,2 � 234,4</span></p>
  </td>
  <td width=132 style='width:99.35pt;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt'></td>
 </tr>
</table>

<p class=MsoListParagraphCxSpFirst style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpMiddle style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoListParagraphCxSpLast style='text-align:justify;line-height:200%'><span
lang=EN-US style='font-size:10.0pt;line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><a name="_Hlk112151843"></a><a
name="_Hlk112152057"><b><span lang=EN-US style='line-height:200%;font-family:
"Times New Roman",serif'>Table 2</span></b></a><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>. DFS and OS
times, comparative Log-rank test, p-value values of Non-Special Type BC and
Non-Lobular Special Type BC, ILC subgroups obtained using Kaplan-Meier method</span></p>

<table class=DzTablo51 border=0 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse'>
 <tr style='height:22.5pt'>
  <td width="26%" rowspan=2 style='width:26.56%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><a
  name="_Hlk112151994"><b><span lang=EN-US style='line-height:115%;font-family:
  "Times New Roman",serif;color:black'>DFS</span></b></a></p>
  </td>
  <td width="12%" rowspan=2 style='width:12.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'></td>
  <td width="17%" rowspan=2 style='width:17.2%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type BC (IDC)</span></b></p>
  </td>
  <td width="23%" rowspan=2 style='width:23.44%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Lobular Special Type BC</span></b></p>
  </td>
  <td width="20%" rowspan=2 style='width:20.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lobular Special Type BC (ILC)</span></b></p>
  </td>
  <td style='height:22.5pt;border:none' width=0 height=30></td>
 </tr>
 <tr style='height:22.5pt'>
  <td style='height:22.5pt;border:none' width=0 height=30></td>
 </tr>
 <tr style='height:25.5pt'>
  <td width="26%" style='width:26.56%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><i><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>P</span></i></b><b><span lang=EN-US style='line-height:115%;
  font-family:"Times New Roman",serif;color:black'> value</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mean�SD</span></p>
  </td>
  <td width="17%" style='width:17.2%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>226,5 � 3,4</span></p>
  </td>
  <td width="23%" style='width:23.44%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>216,7�8,7</span></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>197,2 � 8,9</span></p>
  </td>
  <td style='height:25.5pt;border:none' width=0 height=34></td>
 </tr>
 <tr style='height:25.5pt'>
  <td width="26%" style='width:26.56%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Long-rank test)</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>95% CI</span></p>
  </td>
  <td width="17%" style='width:17.2%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>219,8-233,1</span></p>
  </td>
  <td width="23%" style='width:23.44%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>199,6-233,7</span></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>179,6 � 214,7</span></p>
  </td>
  <td style='height:25.5pt;border:none' width=0 height=34></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="26%" rowspan=3 style='width:26.56%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type BC (IDC)</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lobular Special Type BC</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(ILC)</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="17%" style='width:17.2%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="23%" rowspan=2 style='width:23.44%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.020</span></b></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="12%" style='width:12.5%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.2%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="20%" style='width:20.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:30.75pt'>
  <td width="12%" style='width:12.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'></td>
  <td width="17%" style='width:17.2%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.717</span></p>
  </td>
  <td width="23%" style='width:23.44%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.029</span></b></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'></td>
  <td style='height:30.75pt;border:none' width=0 height=41></td>
 </tr>
 <tr style='height:25.5pt'>
  <td width="26%" rowspan=2 style='width:26.56%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>OS</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mean�SD</span></p>
  </td>
  <td width="17%" style='width:17.2%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>233,2 � 3,5</span></p>
  </td>
  <td width="23%" style='width:23.44%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>227,9 � 7,9</span></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>209,8�8,7</span></p>
  </td>
  <td style='height:25.5pt;border:none' width=0 height=34></td>
 </tr>
 <tr style='height:26.25pt'>
  <td width="12%" style='width:12.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>95% CI</span></p>
  </td>
  <td width="17%" style='width:17.2%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>226,3 � 240,1</span></p>
  </td>
  <td width="23%" style='width:23.44%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>212,3 � 243,5</span></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>192,6-227,0</span></p>
  </td>
  <td style='height:26.25pt;border:none' width=0 height=35></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="26%" style='width:26.56%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Special Type BC (IDC)</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="17%" style='width:17.2%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="23%" style='width:23.44%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.024</span></b></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.504</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="26%" style='width:26.56%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lobular Special Type BC (ILC)</span></b></p>
  </td>
  <td width="12%" style='width:12.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.2%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="23%" style='width:23.44%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.018</span></b></p>
  </td>
  <td width="20%" style='width:20.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt'><a name="_Hlk112152298"><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>DFS:
Disease free survival, OS: Overall survival, SD: Standard deviation, CI:
Confidence Interval</span></a></p>

<p class=MsoNormal align=center style='margin-bottom:8.0pt;text-align:center'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><a
name="_Hlk112152362"><b><span lang=EN-US style='line-height:150%;font-family:
"Times New Roman",serif'>&nbsp;</span></b></a></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><b><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>Table
3. </span></b><span lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>Distribution
of patient characteristics</span></p>

<table class=DzTablo51 border=0 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse'>
 <tr style='height:33.35pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:33.35pt'><a
  name="_Hlk105445237"></a></td>
  <td width="33%" colspan=2 style='width:33.2%;padding:0cm 5.4pt 0cm 5.4pt;
  height:33.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Special Type BC</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(IDC)</span></b></p>
  </td>
  <td width="25%" colspan=2 style='width:25.48%;padding:0cm 5.4pt 0cm 5.4pt;
  height:33.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Invasive Lobular Special Type BC</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(ILC)</span></b></p>
  </td>
  <td width="23%" colspan=2 style='width:23.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:33.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-lobular Special Type BC</span></b></p>
  </td>
 </tr>
 <tr style='height:16.25pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&nbsp;</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N</span></b></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>%</span></b></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>n</span></b></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>%</span></b></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>n</span></b></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:16.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>%</span></b></p>
  </td>
 </tr>
 <tr style='height:14.9pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Gender</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.9pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Female</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1800</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>193</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>100</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>150</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99.33</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Male</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Age</span></b></p>
  </td>
  <td width="19%" rowspan=2 style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>92</span></p>
  </td>
  <td width="13%" rowspan=2 style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5.10%</span></p>
  </td>
  <td width="19%" rowspan=2 style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11</span></p>
  </td>
  <td width="6%" rowspan=2 style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5.7</span></p>
  </td>
  <td width="16%" rowspan=2 style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9</span></p>
  </td>
  <td width="7%" rowspan=2 style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;35</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>35-50</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>696</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>85</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>44</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>58</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;50</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1026</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>56.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>97</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>83</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Menstruation State</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Premenopausal</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>701</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>81</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>36.2</span></p>
  </td>
 </tr>
 <tr style='height:23.0pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Postmenopausal</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1099</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>61.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>112</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>58</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>95</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>63.8</span></p>
  </td>
 </tr>
 <tr style='height:45.4pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Presence of Family History</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>536</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>37</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:45.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>24.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Histological Type</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IDC</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1761</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>97.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>ILC</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>138</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>71.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IDC+ILC</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mucinous</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>44</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Medullary</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>34</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Papillary</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tubular</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Adenoid Cystic</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Secretory</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Apocrine</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Metaplastic</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
 </tr>
 <tr style='height:19.5pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Epidermoid</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'></td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'></td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'></td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'></td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:30.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Right</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>869</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>103</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>69</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:30.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46</span></p>
  </td>
 </tr>
 <tr style='height:33.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Left</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>885</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>75</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:33.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50</span></p>
  </td>
 </tr>
 <tr style='height:28.5pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4.1</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:28.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tumor������ Quadrant***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Inner</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>351</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>44</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Outer</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1085</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>104</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53.9</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>89</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59.3</span></p>
  </td>
 </tr>
 <tr style='height:26.25pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Periareolar</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>239</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multifocal</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>139</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tm Size*</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T1</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>609</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>34</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T2</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>948</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>52.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>98</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>80</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T3</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>135</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13.5</span></b></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T4</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>122</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.7</span></p>
  </td>
 </tr>
 <tr style='height:25.5pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Number of Infiltrated Axillary Nodes**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:25.5pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>736</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>74</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>90</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1-3</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>476</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4-9</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>394</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>32</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14</span></p>
  </td>
 </tr>
 <tr style='height:11.9pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8805;10</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>208</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:11.9pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Stage*, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>I</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>366</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19.7</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>41</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>II</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>778</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>78</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>75</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>III</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>538</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>66</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>34.2</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IV</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>132</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5.7</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Site of Metastasis</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>None</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1460</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>80.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>152</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>78.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>89.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bone</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>123</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lung</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Liver</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Brain</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.7</span></p>
  </td>
 </tr>
 <tr style='height:15.35pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multiple</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>181</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.35pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Surgery Type</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&nbsp;</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>MRM</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>834</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>98</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33.8</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>BCS</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>907</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>52.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>92</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>98</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>66.2</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal style='line-height:115%'><b><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>AxillarySurgery
  Type</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>SLND</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>435</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30.4</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AC</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1306</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>75</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>142</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>74.7</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>103</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>69.6</span></p>
  </td>
 </tr>
 <tr style='height:30.25pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Skin Infiltration</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>147</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4.7</span></p>
  </td>
 </tr>
 <tr style='height:34.95pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive Surgical Margin </span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>337</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>41</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.2</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:34.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Histological Grade*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>219</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>859</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>111</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>36.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>736</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mitotic index</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>285</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>41</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.2</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>37</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>24.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>895</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>49.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>52.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>634</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>35</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>34</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22.7</span></p>
  </td>
 </tr>
 <tr style='height:23.95pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>ER Positive</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1434</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>177</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>91.7</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>101</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:23.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>67.3</span></p>
  </td>
 </tr>
 <tr style='height:27.85pt'>
  <td width="17%" style='width:17.74%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PR Positive</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1175</span></p>
  </td>
  <td width="13%" style='width:13.3%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>64.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>165</span></p>
  </td>
  <td width="6%" style='width:6.42%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>85.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>81</span></p>
  </td>
  <td width="7%" style='width:7.34%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:27.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ki67</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;15</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>603</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>44.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>65</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8805;15</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1209</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>66.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>107</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>85</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>56.7</span></p>
  </td>
 </tr>
 <tr style='height:22.05pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2 Positive</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>459</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>24</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16.7</span></p>
  </td>
 </tr>
 <tr style='height:20.15pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>EIC Positive</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>309</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>17</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>17.1</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.7</span></p>
  </td>
 </tr>
 <tr style='height:18.25pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>LVI Positive</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>881</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30</span></p>
  </td>
 </tr>
 <tr style='height:23.45pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PNI Positive</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>342</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>24.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:23.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Subgroup</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:20.45pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2 enriched</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>138</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:20.45pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Triple Negative</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>207</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4.7</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>37</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>24.7</span></p>
  </td>
 </tr>
 <tr style='height:20.95pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal A</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>483</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.9</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:20.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>33.3</span></p>
  </td>
 </tr>
 <tr style='height:25.4pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal B</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>986</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>103</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:25.4pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>35.3</span></p>
  </td>
 </tr>
 <tr style='height:42.2pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Anti-Hormonal Treatment Received</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1467</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>80.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>181</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>93.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>103</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:42.2pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>68.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of TAM Use</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1051</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>97</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>101</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>67.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>679</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>37.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>84</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>7.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of AI Use</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A*, **</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>734</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30.6</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>72</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>850</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>113</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>58.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>62</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>41.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>230</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.9</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.7</span></p>
  </td>
 </tr>
 <tr style='height:31.25pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Herceptin *Eligibility</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>380</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>23</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT Received</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1589</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>87.6</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>167</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>129</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT Type</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>215</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11.9</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Only</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>515</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28.4</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>69</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Locoregional</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1084</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59.8</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>124</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>64.2</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>61</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>40.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CT Received</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>303</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Neoadjuvant</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>236</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.4</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Adjuvant</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1275</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>70,3</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>131</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>67.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>97</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>64.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CT Type</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>*, **, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="13%" style='width:13.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="19%" style='width:19.06%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="6%" style='width:6.42%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="16%" style='width:16.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="7%" style='width:7.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>303</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.8</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AC+TXT</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>875</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>74</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>38.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>67</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>44.7</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>FAC-FEC-TAC</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>358</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19.7</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29.5</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal style='line-height:115%'><b><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>FAC,FEC+TXT</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>209</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5.3</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal style='line-height:115%'><b><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>Ribociclib+Palbociclib</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Pertuzumab</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.2</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>0</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CMF</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>41</span></p>
  </td>
  <td width="13%" style='width:13.3%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.3</span></p>
  </td>
  <td width="19%" style='width:19.06%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4</span></p>
  </td>
  <td width="6%" style='width:6.42%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.1</span></p>
  </td>
  <td width="16%" style='width:16.24%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5</span></p>
  </td>
  <td width="7%" style='width:7.34%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.3</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Recurrence</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>372</span></p>
  </td>
  <td width="13%" style='width:13.3%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20.5</span></p>
  </td>
  <td width="19%" style='width:19.06%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45</span></p>
  </td>
  <td width="6%" style='width:6.42%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>23.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19</span></p>
  </td>
  <td width="7%" style='width:7.34%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12.7</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.74%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Death</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>**, ***</span></b></p>
  </td>
  <td width="19%" style='width:19.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>328</span></p>
  </td>
  <td width="13%" style='width:13.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18.1</span></p>
  </td>
  <td width="19%" style='width:19.06%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43</span></p>
  </td>
  <td width="6%" style='width:6.42%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22.3</span></p>
  </td>
  <td width="16%" style='width:16.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16</span></p>
  </td>
  <td width="7%" style='width:7.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.7</span></p>
  </td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>ER:
Estrogen Receptor, PR: Progesterone Receptor, HER2: Human Epidermal Growth
Factor Receptor 2, EIC: Extensive Intraductal Carcinoma, LVI: Lymphovascular
Invasion, PNI: Perineural Invasion, TMX: Tamoxifen, AI: Aromatase Inhibitor,
RT: Radiotherapy, CT: Chemotherapy, <a name="_Hlk107572741">AC: Axillary
Curettage SLND: Sentinel Lymph Node Dissection, AC: Adriamycin,
Cyclophosphamide, TXT: Taxotere, FAC: Cyclophosphamid, Adriamycin,
5-Fulourouracil, FEC: 5-Fulouracil, Epirubicine, Cyclophosphamide, TAC:
Taxotere, Adriamycin, Cyclophosphamid, RIBO+PABLO: Ribociclib+ Palbociclib,
CMF: Cyclophosphamide, Methotrexate, Fluorouracil. * Pairwise comparison of all
three groups with Fisher's exact test (p&lt;.0.5) in terms of patient
characteristics (IDC/ILC). ** Pairwise comparison of all three groups with
Fisher's exact test (p&lt;.0.5) in terms of patient characteristics
(ILC/No-Lobular Special Type). </a></span></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>***
Pairwise comparison of all three groups with Fisher's exact test (p&lt;.0.5) in
terms of patient characteristics (IDC/No-Lobular Special Type</span><span
lang=EN-US style='line-height:150%;font-family:"Times New Roman",serif'>).</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:150%'><a
name="_Hlk112152441"><b><span lang=EN-US style='line-height:150%;font-family:
"Times New Roman",serif'>&nbsp;</span></b></a></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Table 4. </span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Univariate
analysis results affecting DFS</span></p>

<table class=DzTablo41 border=0 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse'>
 <tr style='height:15.0pt'>
  <td width="40%" colspan=2 rowspan=2 style='width:40.16%;border:none;
  border-bottom:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="24%" nowrap colspan=2 style='width:24.26%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Recurrence</span></b></p>
  </td>
  <td width="35%" nowrap colspan=2 style='width:35.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Univariate Cox Regression</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="11%" style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="10%" style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>p</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>HR (95% CI)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Age</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;35</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>83
  (4.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>29(6.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>36-50</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>691
  (40.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>148
  (33.9)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.035</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.652(.438-.970)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&gt;50</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>947
  (55)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>259
  (59.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.557</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.891(.607-1.308)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Gender</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Female</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1714
  (99.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>428
  (98.2)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>3.265(1.622-6.574)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Male</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>7
  (0.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>8
  (1.8)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Menstruation Status</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Premenopausal</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>688
  (40.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>148
  (34.6)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.006</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.320(1.081-1.611)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Postmenopausal</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1026
  (59.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>280
  (65.4)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Family History</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>513
  (29.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>114
  (26.1)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.117</span></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.187(.958-1.469)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1208
  (70.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>322
  (73.9)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Histological</span></b></p>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Subtype Group � 1</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1442
  (83.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>372
  (85.3)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.237</span></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.852(.653-1.1111)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Special Type B</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>279
  (16.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>64
  (14.7)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Histological Subtype Group � 2</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Non-Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1442
  (83.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>372
  (20.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Invasive Lobular Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>148
  (8.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>45
  (10.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.724</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.057(.776-1.441)</span></p>
  </td>
 </tr>
 <tr style='height:43.5pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Non-lobular Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>131
  (7.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>19
  (4.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.022</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.584(.368-.925)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Arrangement</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Unilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1674
  (97.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>409
  (93.8)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.003</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.808(1.225-2.670)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>47
  (2.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>27
  (6.2)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Breast</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Left</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>841
  (48.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>201
  (46.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Right</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>833
  (48.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>208
  (47.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.833</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.021(.841-1.240)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>47
  (2.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>27
  (6.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.003</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.828(1.223-2.732)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" style='width:22.46%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Inner</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>351
  (20.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>84
  (19.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" style='width:22.46%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Outer</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1034
  (60.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>244
  (56)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.954</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.007(.786-1.291)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" style='width:22.46%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Tumor Quadrant</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Periareolar</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>222
  (12.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>57
  (13.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.597</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.095(.782-1.533)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="22%" style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'></td>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Multicentric</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>114
  (6.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>51
  (11.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.876(1.324-2.657)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=4 style='width:22.46%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>T Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>T1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>648
  (37.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>66
  (15.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>T2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>889
  (51.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>237
  (54.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.401(1.827-3.154)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>T3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>131
  (7.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>45
  (10.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.803(1.919-4.095)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>T4</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>53
  (3.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>88
  (20.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>12.650(9.156-17.479)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=4 style='width:22.46%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N0</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>818
  (47.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>82 (18.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>478
  (27.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>86
  (19.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.658(1.225-2.244)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>293
  (17)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>154
  (35.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.000</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>4.808(3.676-6.289)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>132
  (7.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>114
  (26.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.000</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>6.817(5.130-9.060)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=4 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>I</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>422
  (24.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>23
  (5.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>II</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>825
  (47.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>106
  (24.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.181(1.390-3.424)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>III</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>469
  (27.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>164
  (37.6)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>5.605(3.622-8.672)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>IV</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>5
  (0.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>143
  (32.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>104.241(66.093-164.408)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=6 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Site of Metastasis</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1719
  (99.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>27
  (6.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Bone</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1
  (0.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>145
  (33.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>167.63(110.55-254.18)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Lung</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>0
  (0)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>23
  (5.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>159.811(90.86-281.08)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Liver</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>0
  (0)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>14
  (3.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>174.24(90.66-334.87)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Brain</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>0
  (0)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>24
  (5.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>179.70(102.60-314.73)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Multiple</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1
  (0.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>203
  (46.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>171.71(113.89-258.88)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>ER</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1393
  (80.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>319
  (73.2)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.476(1.194-1.824)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>328
  (19.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>117
  (26.8)</span></p>
  </td>
 </tr>
 <tr style='height:18.9pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>PR</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1167
  (67.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>254
  (58.3)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" rowspan=2 style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:18.9pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.499(1.239-1.814)</span></b></p>
  </td>
 </tr>
 <tr style='height:13.95pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>554
  (32.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>182
  (41.7)</span></p>
  </td>
 </tr>
 <tr style='height:20.75pt'>
  <td width="22%" style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>HER2</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>383
  (22.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>125
  (28.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:20.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.668(.542-.823)</span></b></p>
  </td>
 </tr>
 <tr style='height:28.15pt'>
  <td width="22%" style='width:22.46%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>EIC</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1459
  (84.8)</span></p>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>262
  (15.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>340
  (78)</span></p>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>96
  (22)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:28.15pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.536(1.224-1.927)</span></b></p>
  </td>
 </tr>
 <tr style='height:13.95pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>LVI</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>809
  (47)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>216
  (49.5)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.312</span></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.95pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.908(.752-1.095)</span></p>
  </td>
 </tr>
 <tr style='height:5.7pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:5.7pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:5.7pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>912
  (53)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:5.7pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>220
  (50.5)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>PNI</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>311
  (18.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>89
  (20.4)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.580</span></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.936(.742-1.182)</span></p>
  </td>
 </tr>
 <tr style='height:8.0pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:8.0pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:8.0pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1410
  (81.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:8.0pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>347
  (79.6)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Ki67</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;15</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>670 (39)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>84
  (19.3)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.481(1.955-3.148)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&#8805;15</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1049
  (61)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>352
  (80.7)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Mitotic Index</span></b></p>
  </td>
  <td width="17%" nowrap style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>342
  (19.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>21
  (4.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" nowrap style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>913
  (53.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>160
  (36.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.739(1.738-4.318)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" nowrap style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>466
  (27.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>255
  (58.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>8.114(5.197-12.669)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Histologic Grade</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Grade I</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>261 (15.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>28
  (6.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Grade II</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>845
  (49.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>180
  (41.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.002</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.877(1.261-2.795)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Grade III</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>615
  (35.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>228
  (52.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>3.223(2.176-4.774)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Skin Infiltration</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>82
  (4.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>86
  (19.7)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.214(.168-.272)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1639
  (95.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>350
  (80.3)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Surgical Margin</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1387
  (80.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>365
  (83.7)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.664</span></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;padding:
  0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.945(.732-1.219)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>334
  (19.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>71
  (16.3)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Subgroup (Luminal)</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Luminal A-B</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1422
  (82.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>332
  (76.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Triple Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>199
  (11.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>54
  (12.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.406</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.130(.847-1.506)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>HER2 Enriched</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>100
  (5.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>50
  (11.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.139(1.588-2.881)</span></b></p>
  </td>
 </tr>
 <tr style='height:26.45pt'>
  <td width="22%" rowspan=4 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Subgroup</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>HER2 Enriched</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>100
  (5.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>50
  (11.5)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Triple Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>199
  (11.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>54
  (12.4)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.527(.359-.775)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Luminal A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>547
  (31.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>65
  (14.9)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.246(.170-.356)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Luminal B</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>875
  (50.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>267 (61.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.597(.441-.808)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Surgery</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>8
  (0.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>70
  (16.1)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.054(.041-.071)</span></b></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1713
  (99.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>366
  (83.9)</span></p>
  </td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Breast Surgery Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>BCS</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>970
  (56.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>127
  (34.7)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2.049(1.652-2.542)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>MRM</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>743
  (43.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>239
  (65.3)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>8
  (0.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>70 (16.1)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.054(.041-.071)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1713
  (99.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>366
  (83.9)</span></p>
  </td>
 </tr>
 <tr style='height:22.5pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>SLND</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>481
  (28.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>47
  (12.8)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.966(1.445-2.674)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>AK</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1232
  (71.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>319
  (87.2)</span></p>
  </td>
 </tr>
 <tr style='height:22.5pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Anti-Hormonal Treatment</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1419
  (82.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>332
  (76.1)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>1.454(1.167-1.813)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>302
  (17.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>104
  (23.9)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Duration of TAM Use</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1059
  (61.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>190
  (43.6)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:19.5pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>570
  (33.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>234
  (53.7)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.000</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.5pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.885(1.555-2.284)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>92
  (5.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>12
  (2.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.071</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.584(.326-1.047)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Duration of AI Use</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>669 (38.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>196
  (45)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>819
  (47.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>206
  (47.2)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.075</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.837(.688-1.018)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>233
  (13.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>34
  (7.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.429(.298-.619)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>RT</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1579
  (91.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>306
  (70.2)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>3.580(2.914-4.398)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>142
  (8.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>130
  (29.8)</span></p>
  </td>
 </tr>
 <tr style='height:17.1pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>RT Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>134
  (7.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>127
  (29.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.1pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:14.3pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:14.3pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Breast Only</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.3pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>580
  (33.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.3pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>47
  (10.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.3pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.3pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.124(.089-.174)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Locoregional</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1007
  (58.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>262
  (60.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.350
  (.283-.433)</span></p>
  </td>
 </tr>
 <tr style='height:19.2pt'>
  <td width="22%" rowspan=2 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Herceptin Eligibility</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Eligible</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>331
  (19.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>92
  (21.1)</span></p>
  </td>
  <td width="10%" nowrap rowspan=2 style='width:10.6%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.023</span></b></p>
  </td>
  <td width="24%" nowrap rowspan=2 style='width:24.98%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.2pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>.765(.607-.965)</span></b></p>
  </td>
 </tr>
 <tr style='height:21.35pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:21.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Ineligible</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:21.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1390
  (80.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:21.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>344 (78.9)</span></p>
  </td>
 </tr>
 <tr style='height:13.35pt'>
  <td width="22%" rowspan=3 style='width:22.46%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>CT</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>318
  (18.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>46
  (10.6)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:13.35pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:14.05pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:14.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Neoadjuvant</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>184
  (10.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>82
  (18.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>2.812(1.959-4.035)</span></p>
  </td>
 </tr>
 <tr style='height:14.25pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:14.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Adjuvant</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1219
  (70.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>308
  (70.6)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.025</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.25pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.424(1.044-1.943)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="22%" rowspan=7 style='width:22.46%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>CT</span></b></p>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>328
  (19.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>60
  (13.8)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>AC+TXT</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>863
  (50.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>153
  (35.1)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.986</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.997(.740-1.344)</span></p>
  </td>
 </tr>
 <tr style='height:17.8pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:17.8pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>FAC-FEC-TAC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.8pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>310
  (18)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.8pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>132
  (30.3)</span></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.8pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.015</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:17.8pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>1.465(1.077-1.994)</span></p>
  </td>
 </tr>
 <tr style='height:14.45pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:14.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>FAC-FEC+TXT</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>189 (11)</span></b></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>44 (10.1)</span></b></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.932</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:14.45pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>.983(.666-1.452)</span></p>
  </td>
 </tr>
 <tr style='height:19.05pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:19.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>RIBO+PABLO</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>0 (0)</span></b></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>6 (1.4)</span></b></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:19.05pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>20.437(8.755-47.704)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>PERJETA</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>2 (0.1)</span></b></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>20 (4.6)</span></b></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>16.309(9.751-27.276)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>CMF</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>29 (1.7)</span></b></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><b><span
  lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif;
  color:black'>21 (4.8)</span></b></p>
  </td>
  <td width="10%" nowrap style='width:10.6%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>&lt;.001</span></p>
  </td>
  <td width="24%" nowrap style='width:24.98%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center'><span lang=EN-US
  style='line-height:200%;font-family:"Times New Roman",serif;color:black'>2.663(1.619-4.379)</span></p>
  </td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt;text-align:justify;line-height:
115%'><span lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>ER:
Estrogen Receptor, PR: Progesterone Receptor, HER2: Human Epidermal Growth
Factor Receptor 2, EIC: Extensive Intraductal Carcinoma, LVI: Lymphovascular
Invasion, PNI: Perineural Invasion, TMX: Tamoxifen, AI: Aromatase Inhibitor,
RT: Radiotherapy, CT: Chemotherapy, AC: Axillary Curettage, SLND: Sentinel
Lymph Node Dissection, AC: Adriamycin, Cyclophosphamide, TXT: Taxotere, FAC:
Cyclophosphamid, Adriamycin, 5-Fulourouracil, FEC: 5-Fulouracil, Epirubicine,
Cyclophosphamide, TAC: Taxotere, Adriamycin, Cyclophosphamid, RIBO+PABLO:
Ribociclib+ Palbociclib, CMF: Cyclophosphamide, Methotrexate, Fluorouracil</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt;text-align:justify'><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><a name="_Hlk112152482"><b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Table
5. </span></b></a><span lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Multivariate
analysis results affecting DFS</span></p>

<table class=DzTablo41 border=0 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse'>
 <tr style='height:15.75pt'>
  <td width="45%" colspan=2 rowspan=2 style='width:45.48%;border:none;
  border-bottom:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="24%" nowrap colspan=2 style='width:24.26%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Recurrence</span></b></p>
  </td>
  <td width="30%" nowrap colspan=2 style='width:30.26%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multivariate Cox Regression</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="11%" style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>p</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HR (95% CI)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Age</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;35</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>83 (4.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>29 (6.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>36-50</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>691 (40.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>148 (33.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.05</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.629(.395-1.000)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;50</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>947 (55)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>259 (59.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.175</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.671(.377-1.194)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Menstruation Status</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Premenopausal</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>688 (40.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>148 (34.6)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.<b>025</b></span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.524(1.054-2.205)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Postmenopausal</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1026 (59.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>280 (65.4)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Histological Subtype Group- 2</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1442 (83.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>372 (85.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:26.25pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Invasive Lobular Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>148 (8.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45 (10.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.766</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.053(.748-1.483)</span></p>
  </td>
 </tr>
 <tr style='height:26.25pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Lobular Special Type BC</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>131 (7.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>19 (4.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.589</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:26.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.871(.529-1.436)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Arrangement</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Unilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1674 (97.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>409 (93.8)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.004</span></b></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.265(1.306-3.927)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47 (2.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27 (6.2)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Location of BC</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Left</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>841 (48.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>201 (46.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47 (2.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27 (6.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.004</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.265(1.306-3.927)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multicentric</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>114 (6.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51 (11.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.053</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.874(762-1.001)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=4 style='width:27.78%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>648 (37.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>66 (15.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>889 (51.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>237 (54.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.003</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.737(1.214-2.486)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>131 (7.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45 (10.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.156</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.417(.875-2.295)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T4</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53 (3.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>88 (20.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.015</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.059(1.154-3.675)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=4 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N0</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>818 (47.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82 (18.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>478 (27.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86 (19.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.226</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.304(.849-2.002)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>293 (17)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>154 (35.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.269</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.349(.793-2.296)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>132 (7.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>114 (26.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.232</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.396(.808-2.413)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=4 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Stage</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>I</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>422 (24.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>23 (5.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>II</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>825 (47.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>106 (24.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.433</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.265(.703-2.279)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>III</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>469 (27.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>164 (37.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.021</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.275(1.129-4.583)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IV</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5 (0.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>143 (32.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>32.105(15.256-67.563)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>ER</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1393 (80.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>319 (73.2)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.086</span></b></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.688(.928-3.071)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>328 (19.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>117 (26.8)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PR</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1167 (67.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>254 (58.3)</span></p>
  </td>
  <td width="7%" rowspan=2 style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.651</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.071(.796-1.442)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>554 (32.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>182 (41.7)</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2</span></b></p>
  </td>
  <td width="17%" rowspan=3 style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="12%" nowrap rowspan=3 style='width:12.68%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>383 (22.3)</span></p>
  </td>
  <td width="11%" nowrap rowspan=3 style='width:11.58%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>125 (28.7)</span></p>
  </td>
  <td width="7%" style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'></td>
  <td width="22%" rowspan=3 style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.536(.358-.802)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="7%" style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.002</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="7%" style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ki67</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;15</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>670 (39)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>84 (19.3)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.622</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.076(.804-1.440)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8805;15</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1049 (61)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>352 (80.7)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mitotic Index</span></b></p>
  </td>
  <td width="17%" nowrap style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>342 (19.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21 (4.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" nowrap style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>913 (53.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>160 (36.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.009</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.951(1.180-3.224)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" nowrap style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>466 (27.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>255 (58.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.753(1.607-4.715)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tm Grade</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade I</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>261 (15.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>28 (6.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade II</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>845 (49.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>180 (41.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.154</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.416(.878-2.283)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade III</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>615 (35.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>228 (52.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.384</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.257(.751-2.102)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Skin Infiltration</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82 (4.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86 (19.7)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.237</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.753(.470-1.205)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1639 (95.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>350 (80.3)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>EIC</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1459 (84.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>340 (78)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.112</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.243(.950-1.627)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>262 (15.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>96 (22)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=4 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Subgroup</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2 Enriched</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>100 (5.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>50 (11.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Triple Negative</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>199 (11.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>54 (12.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>547 (31.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>65 (14.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal B</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>875 (50.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>267 (61.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Surgery Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>BCS</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>970 (56.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>127 (34.7)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.356</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.131(.871-1.468)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>MRM</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>743 (43.4)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>239 (65.3)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>SLND</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>481 (28.1)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47 (12.8)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.267</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.813(.563-1.172)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AK</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1232 (71.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>319 (87.2)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Anti-Hormonal Treatment</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1419 (82.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>332 (76.1)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.437</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.737(.342-1.590)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>302 (17.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>104 (23.9)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=4 style='width:27.78%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of TAM Use</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1059 (61.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>190 (43.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="12%" nowrap rowspan=2 style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>570 (33.1)</span></p>
  </td>
  <td width="11%" nowrap rowspan=2 style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>234 (53.7)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.021</span></b></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.499(1.062-2.117)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>92 (5.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>12 (2.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.642</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.847(.421-1.704)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of AI Use</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>669 (38.9)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>196 (45)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>819 (47.6)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>206 (47.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.249</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.824(.593-1.145)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>233 (13.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>34 (7.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.047</span></b></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.607(.371-.993)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1579 (91.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>306 (70.2)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.524</span></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.631(.153-2.607)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>142 (8.3)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>130 (29.8)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT Type</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134 (7.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>127 (29.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Only</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>580 (33.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>47 (10.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.222</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.397(.090-1.747)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Locoregional</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1007 (58.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>262 (60.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.174</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.367(.086-1.558)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=2 style='width:27.78%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Herceptin Eligibility</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Eligible</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>331 (19.2)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>92 (21.1)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.5%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.032</span></b></p>
  </td>
  <td width="22%" nowrap rowspan=2 style='width:22.76%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.638(1.043-2.572)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ineligible</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1390 (80.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>344 (78.9)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="27%" rowspan=3 style='width:27.78%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CT Received</span></b></p>
  </td>
  <td width="17%" style='width:17.7%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>318 (18.5)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46 (10.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Neadjuvant</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>184 (10.7)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82 (18.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.586</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.151(.694-1.911)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.7%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Adjuvant</span></b></p>
  </td>
  <td width="12%" nowrap style='width:12.68%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1219 (70.8)</span></p>
  </td>
  <td width="11%" nowrap style='width:11.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>308 (70.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.5%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.119</span></p>
  </td>
  <td width="22%" nowrap style='width:22.76%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.708(.459-1.093)</span></p>
  </td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>ER: Estrogen
Receptor, PR: Progesterone Receptor, HER2: Human Epidermal Growth Factor Receptor
2, EIC: Extensive TMX: Tamoxifen, AI: Aromatase Inhibitor, RT: Radiotherapy,
CT: Chemotherapy, AC: Axillary Curettage SLND: Sentinel Lymph Node Dissection</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><a name="_Hlk112152633"><b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></b></a></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Table 6. </span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Univariate
analysis results affecting OS</span></p>

<table class=TabloKlavuzu1 border=1 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse;border:none'>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="30%" colspan=2 style='width:30.36%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Survival Status </span></b><span lang=EN-US style='line-height:
  115%;font-family:"Times New Roman",serif'>[n (%)]</span></p>
  </td>
  <td width="32%" colspan=2 style='width:32.52%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Univariate Cox Regression</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Alive</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Deceased</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>p</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HR (95% CI)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Age</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;35</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>87 (4.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25 (6.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:12.05pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:12.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>36-50</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:12.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>722 (40.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:12.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>117 (30.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:12.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.013</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:12.05pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.577(.375-.889)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;50</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>961 (54.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>245 (63.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.894</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.028(.681-1.552)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Gender</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Female</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1761 (99.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>381 (98.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.014</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.753(1.228-6.168)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Male</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9 (0.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>6 (1.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Menstruation State</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Premenopausal</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>718 (40.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>118 (31)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.664(1.338-2.068)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.0pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Postmenopausal</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1043 (59.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>263 (69)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.0pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Family History</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>536 (30.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>91 (23.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.005</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.402(1.108-1.773)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1234 (69.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>296 (76.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Histological Subtype� Group- 1</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1486</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>328</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.379</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.883(.669-1.165)</span></p>
  </td>
 </tr>
 <tr style='height:32.15pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:32.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Special Type</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:32.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>284</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:32.15pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>59</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:32.15pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:32.15pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Histological Subtype� Group- 2</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1486</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>328 (84.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Invasive Lobular BC</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>150</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43 (11.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.502</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.115(.811-1.532)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-lobular Special Type BC</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134 (7.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16 (4.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.026</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.566(.343-.935)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>Arrangement</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Unilateral</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1713 (96.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>370 (95.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.690</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.104(.679-1.795)</span></p>
  </td>
 </tr>
 <tr style='height:30.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57 (3.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>17 (4.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:30.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Left</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>855 (48.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>187 (48.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Right</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>858 (48.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>183 (47.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.695</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.960(.783-1.177)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bilateral</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>57 (3.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>17 (4.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.757</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.082(.658-1.777)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tumor Quadrant</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Inner</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>356 (20.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79 (20.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Outer</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1052 (59.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>226 (58.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.962</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.994(.769-1.284)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Areola</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>234 (13.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>45 (11.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.667</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.923(.640-1.331)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multicentric</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>128 (7.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>37 (9.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.074</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.428(.966-2.110)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T Stage</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T1</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>654 (36.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60 (15.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T2</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>920 (52)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>206 (53.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.212(1.659-2.949)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T3</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134 (7.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42 (10.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.636(1.777-3.912)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T4</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>62 (3.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79 (20.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>13.115(9.330-18.436)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N Stage</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N0</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>804 (45.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>96 (24.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N1</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>490 (27.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>74 (19.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.338</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.160(.856-1.571)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N2</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>319 (18)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>128 (33.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.398(2.607-4.429)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N3</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>157 (8.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>89 (23)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4..318(3.234-5.764)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Stage</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>I</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>420 (23.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25 (6.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>II</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>812 (45.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>119 (30.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.113(1.373-3.252)</span></b></p>
  </td>
 </tr>
 <tr style='height:10.6pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:10.6pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>III</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:10.6pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>470 (26.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:10.6pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>163 (42.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:10.6pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:10.6pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4.783(3.139-7.286)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IV</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>68 (3.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>80 (20.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>21.748(13.828-34.204)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Metastatic Site</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1621 (91.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>125 (32.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bone</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>69 (3.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>77 (19.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9.199(6.922-12.226)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lung</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9 (0.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14 (3.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.972(6.311-19.075)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Liver</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4 (0.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10 (2.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>17.278(9.058-32.959)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Brain</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2 (0.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22 (5.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26.432(16.733-41.753)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multiple</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>65 (3.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>139 (35.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15.046(11.794-19.193)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Surgery</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30 (1.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48 (12.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.091(.067-.125)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1740 (98.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>339 (87.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Surgery Type</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>BCS</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>998 (57.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99 (29.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal style='line-height:115%'><b><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>2.385(1.887-3.016)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>MRM</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>742 (42.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>240 (70.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30 (1.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48 (12.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.091(.067-.125)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1740 (98.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>339 (87.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery</span></b></p>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Type</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>SLND</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>497 (28.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>31 (9.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal style='line-height:115%'><b><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>2.298(1.586MNNMZ3.331)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AC</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1243 (71.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>308 (90.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Skin Infiltration</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86 (4.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82 (21.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.170(.132-.218)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1684 (95.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>305 (78.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Surgical Margin</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1441 (81.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>311 (80.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.023</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.340(1.042-1.723)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>329 (18.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>76 (19.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tm Grade</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade I</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>286 (16.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3 (0.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade II</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>866 (48.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>159 (41.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>15.313(4.886-47.986)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade III</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>618 (34.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>225 (58.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>30.243(9.680-94.487)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mitotic Index</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>360 (20.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3 (0.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>918 (51.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>155 (40.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>18.444(5.884-57.817)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>492 (27.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>229 (59.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>51.199(16.389-159.950)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>ER</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1438 (81.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>274 (70.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.675(1.345-2.085)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>332 (18.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>113 (29.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PR</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1194 (67.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>227 (58.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.537(1.255-1.881)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>576 (32.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>160 (41.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>406 (22.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>102 (26.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.002</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.697(.555-.876)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1364 (77.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>285 (73.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ki67</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;15</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>681 (38.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>73 (18.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.493(1.932-3.217)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8805;15</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1087 (61.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>314 (81.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>EIC</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1502 (84.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>297 (76.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.678(1.325-2.125)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>268 (15.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>90 (23.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>LVI</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>827 (46.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>198 (51.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.078</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.836(.685-1.020)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>943 (53.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>189 (48.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PNI</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>314 (17.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86 (22.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.313</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.884(.695-1.123)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1456 (82.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>301 (77.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Subgroup Luminal</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal A-B</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1468 (82.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>286 (73.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Triple negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>198 (11.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55 (14.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.034</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.366(1.023-1.823)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2 enriched</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>104 (5.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46 (11.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.415(1.767-3.301)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Subgroup</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2 enriched</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>104 (5.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>46 (11.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Triple negative</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>198 (11.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55 (14.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.004</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.565(.381-.836)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>559 (31.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53 (13.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.209(.141-.310)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Luminal B</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>909 (51.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>233 (60.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.532(.387-.731)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Anti-Hormonal Treatment</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1466 (82.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>285 (73.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.723(1.374-2.160)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>304 (17.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>102 (26.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of TAM Use</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1034 (58.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>215 (55.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>640 (36.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>164 (42.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.938</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.008(.822-1.237)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>96 (5.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8 (2.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.294(.145-.595)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of AI Use</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>691 (39)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>174 (45)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>832 (47)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>193 (49.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.116</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.848(.691-1.041)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>247 (14)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20 (5.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.237(.149-.377)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Herceptin Eligibility</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Eligible</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>361 (20.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>62 (16)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.665</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.941(.715-1.239)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ineligible</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1409 (79.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>325 (84)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.9%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1591 (89.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>294 (76)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.380(1.884-3.006)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>179 (10.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>93 (24)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT Type</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>171 (9.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>90 (23.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Only</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>574 (32.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53 (13.7)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.236(.168-.331)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Locoregional </span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1025 (57.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>244 (63)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.506(.397-.645)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.9%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CT</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>316 (17.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48 (12.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Neadjuvant</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>206 (11.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60 (15.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.002</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.839(1.258-2.689)</span></b></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Adjuvant</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1248 (70.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>279 (72.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.864</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.027(.756-1.396)</span></p>
  </td>
 </tr>
 <tr style='height:31.85pt'>
  <td width="17%" rowspan=7 style='width:17.9%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CT Type</span></b></p>
  </td>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>333 (18.8)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>55 (14.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.85pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AC+TXT</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>888 (50.2)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>128 (33.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.503</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.898(.654-1.232)</span></p>
  </td>
 </tr>
 <tr style='height:36.95pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:36.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>FAC-FEC-TAC</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:36.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>312 (17.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:36.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>130 (33.6)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:36.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.378</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:36.95pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.154(.839-1.587)</span></p>
  </td>
 </tr>
 <tr style='height:34.65pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:34.65pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>FAC-FEC+TXT</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:34.65pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>185 (10.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:34.65pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48 (12.4)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:34.65pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.815</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:34.65pt'>
  <p class=MsoNormal style='line-height:115%'><span lang=EN-US
  style='line-height:115%;font-family:"Times New Roman",serif;color:black'>����
  .955(.647-������� 1.408)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><a
  name="_Hlk108036163"><b><span lang=EN-US style='line-height:115%;font-family:
  "Times New Roman",serif;color:black'>RIBO+PABLO</span></b></a></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>5 (0.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1 (0.3)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.268</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.061(.423-22.183)</span></p>
  </td>
 </tr>
 <tr style='height:31.25pt'>
  <td width="19%" style='width:19.24%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PERJETA</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20 (1.1)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2 (0.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.905</span></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:31.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.090(.265-4.476)</span></p>
  </td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="19%" style='width:19.24%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>CMF</span></b></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>27 (1.5)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>23 (5.9)</span></p>
  </td>
  <td width="15%" style='width:15.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="17%" style='width:17.34%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.627(1.613-4.279)</span></b></p>
  </td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt;text-align:justify;line-height:
115%'><span lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>ER:
Estrogen Receptor, PR: Progesterone Receptor, HER2: Human Epidermal Growth
Factor Receptor 2, EIC: Extensive Intraductal Carcinoma, LVI: Lymphovascular
Invasion, PNI: Perineural Invasion, TMX: Tamoxifen, AI: Aromatase Inhibitor,
RT: Radiotherapy, CT: Chemotherapy, AC: Axillary Curettage, SLND: Sentinel
Lymph Node Dissection, <a name="_Hlk108036701">AC: Adriamycin,
Cyclophosphamide, TXT: Taxotere, FAC: </a><a name="_Hlk108034763">Cyclophosphamid,</a>
Adriamycin, 5-Fulourouracil, FEC: 5-Fulouracil, Epirubicine, Cyclophosphamide,
TAC: Taxotere, Adriamycin, Cyclophosphamid, RIBO+PABLO:Ribociclib+Palbociclib,
CMF: Cyclophosphamide, Methotrexate, Fluorouracil</span><a name="_Hlk112152729"></a></p>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:115%'><b><span
lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>Table
7. </span></b><span lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>Multivariate
analysis results affecting OS</span></p>

<table class=DzTablo41 border=0 cellspacing=0 cellpadding=0 width="100%"
 style='width:100.0%;border-collapse:collapse'>
 <tr style='height:15.75pt'>
  <td width="35%" colspan=2 rowspan=2 style='width:35.88%;border:none;
  border-bottom:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'></td>
  <td width="32%" nowrap colspan=2 style='width:32.34%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Survival Status</span></b></p>
  </td>
  <td width="31%" nowrap colspan=2 style='width:31.78%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multivariate Cox Regression</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Alive</span></b></p>
  </td>
  <td width="12%" style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Deceased</span></b></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>p</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HR (95% CI)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Age</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;35</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>87 (4.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25 (6.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>36-50</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>722 (40.8)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>117 (30.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.555</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.185(.675-2.079)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;50</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>961 (54.3)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>245 (63.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.168</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.578(.825-3.019)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Menstruation Status</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Premenopausal</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>718 (40.8)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>118 (31)</span></p>
  </td>
  <td width="7%" nowrap rowspan=3 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.981</span></p>
  </td>
  <td width="23%" nowrap rowspan=3 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.005(.675-1.495)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:22.5pt'>
  <td width="18%" rowspan=2 style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Postmenopausal</span></b></p>
  </td>
  <td width="20%" nowrap rowspan=2 style='width:20.18%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1043 (59.2)</span></p>
  </td>
  <td width="12%" nowrap rowspan=2 style='width:12.16%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>263 (69)</span></p>
  </td>
  <td style='height:22.5pt;border:none' width=0 height=30></td>
 </tr>
 <tr style='height:22.5pt'>
  <td style='height:22.5pt;border:none' width=0 height=30></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Family History</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>536 (30.3)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>91 (23.5)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.191</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.205(.911-1.593)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1234 (69.7)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>296 (76.5)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HistologicalSubtype� Group - 2</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>No-Special Type</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1486</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>328 (84.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:29.25pt;border:none' width=0 height=39></td>
 </tr>
 <tr style='height:29.25pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Invasive Lobular BC</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>150</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>43 (11.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.045</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:29.25pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.457(1.009-2.104)</span></b></p>
  </td>
  <td style='height:29.25pt;border:none' width=0 height=39></td>
 </tr>
 <tr style='height:43.5pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Non-Lobular Special Type BC</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134 (7.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>16 (4.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.579</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:43.5pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.861(.507-1.462)</span></p>
  </td>
  <td style='height:43.5pt;border:none' width=0 height=58></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T Stage</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T1</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>654 (36.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60 (15.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T2</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>920 (52)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>206 (53.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.191</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.301(.877-1.929)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T3</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>134 (7.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>42 (10.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.021</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.791(1.094-2.932)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>T4</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>62 (3.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>79 (20.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.005</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.486(1.315-4.700)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N Stage</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N0</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>804 (45.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>96 (24.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N1</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>490 (27.7)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>74 (19.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.790</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.056(.707-1.578)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N2</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>319 (18)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>128 (33.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.002</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.358(1.384-4.018)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N3</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>157 (8.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>89 (23)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.007</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.184(1.243-3.836)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=4 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Stage</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>I</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>420 (23.7)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>25 (6.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>II</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>812 (45.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>119 (30.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.058</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.802(.980-3.314)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>III</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>470 (26.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>163 (42.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.825</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.090(.507-2.343)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>IV</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>68 (3.8)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>80 (20.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.112</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.987(.853-4.631)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Skin Infiltration</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>86 (4.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>82 (21.2)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.034</span></b></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.598(.372-.961)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1684 (95.1)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>305 (78.8)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Surgical Margin</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1441 (81.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>311 (80.4)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.666(1.275-2.176)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>329 (18.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>76 (19.6)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of TAM Use</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1034 (58.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>215 (55.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>640 (36.2)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>164 (42.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.430(.295-.625)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>96 (5.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>8 (2.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.177(.074-.423)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border-top:solid windowtext 1.0pt;
  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Duration of AI Use</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>691 (39)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>174 (45)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-top:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8804; 5 years</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>832 (47)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>193 (49.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.015</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.609(.407-.909)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&gt;5 years</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>247 (14)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>20 (5.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.143(.077-.266)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>ER</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1438 (81.2)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>274 (70.8)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.395</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.307(.706-2.419)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>332 (18.8)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>113 (29.2)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>PR</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1194 (67.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>227 (58.7)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.584</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.910(.650-1.275)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>576 (32.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>160 (41.3)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>HER2</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Positive</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>406 (22.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>102 (26.4)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.197</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.790(.552-1.130)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Negative</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1364 (77.1)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>285 (73.6)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Ki67</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;15</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>681 (38.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>73 (18.9)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.502</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.836(.496-1.410)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&#8805;15</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1087 (61.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>314 (81.1)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Mitotic Index</span></b></p>
  </td>
  <td width="18%" nowrap style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>360 (20.3)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3 (0.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" nowrap style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>918 (51.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>155 (40.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.025</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.616(1.131-6.053)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" nowrap style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>492 (27.8)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>229 (59.2)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.005</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.530(1.475-8.449)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Tm Grade</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade I</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>286 (16.2)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3 (0.8)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade II</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>866 (48.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>159 (41.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.091</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.080(.889-4.868)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Grade III</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>618 (34.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>225 (58.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.025</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.748(1.139-6.631)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Chemotherapy</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>316 (17.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>48 (12.4)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Neoadjuvant</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>206 (11.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>60 (15.5)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.141(.053-.373)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Adjuvant</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1248 (70.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>279 (72.1)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.161(.066-.392)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>EIC</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1502 (84.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>297 (76.7)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.281</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.180(.873-1.595)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>268 (15.1)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>90 (23.3)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Surgery Type</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>BCS</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>998 (57.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>99 (29.2)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.008</span></b></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.546(1.122-2.130)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>MRM</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>742 (42.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>240 (70.8)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.3%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Axillary Surgery</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>SLND</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>497 (28.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>31 (9.1)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.099</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.443(.933-2.234)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Type</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>AK</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1243 (71.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>308 (90.9)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=2 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Present</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1591 (89.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>294 (76)</span></p>
  </td>
  <td width="7%" nowrap rowspan=2 style='width:7.88%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.122</span></p>
  </td>
  <td width="23%" nowrap rowspan=2 style='width:23.92%;border:none;border-bottom:
  solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2.447(.788-7.600)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>179 (10.1)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>93 (24)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=3 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>RT Type</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>171 (9.7)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>90 (23.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Breast Only</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>574 (32.4)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>53 (13.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.026</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>3.729(1.167-11.913)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Locoregional</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1025 (57.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>244 (63)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>.431</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1.609(.492-5.262)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="17%" rowspan=6 style='width:17.3%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Site of Metastasis</span></b></p>
  </td>
  <td width="18%" style='width:18.58%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>N/A</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1621 (91.6)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>125 (32.3)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>1</span></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>(Reference)</span></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Bone</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>69 (3.9)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>77 (19.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9.010(6.481-12.524)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Lung</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>9 (0.5)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14 (3.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10.887(6.034-19.644)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Liver</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>4 (0.2)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>10 (2.6)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>14.829(6.774-32.464)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Brain</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>2 (0.1)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>22 (5.7)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;padding:0cm 5.4pt 0cm 5.4pt;
  height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>26.076(15.484-43.914)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
 <tr style='height:15.75pt'>
  <td width="18%" style='width:18.58%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>Multiple</span></b></p>
  </td>
  <td width="20%" nowrap style='width:20.18%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>65 (3.7)</span></p>
  </td>
  <td width="12%" nowrap style='width:12.16%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>139 (35.9)</span></p>
  </td>
  <td width="7%" nowrap style='width:7.88%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>&lt;.001</span></b></p>
  </td>
  <td width="23%" nowrap style='width:23.92%;border:none;border-bottom:solid windowtext 1.0pt;
  padding:0cm 5.4pt 0cm 5.4pt;height:15.75pt'>
  <p class=MsoNormal align=center style='text-align:center;line-height:115%'><b><span
  lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif;
  color:black'>11.479(5.457-17.249)</span></b></p>
  </td>
  <td style='height:15.75pt;border:none' width=0 height=21></td>
 </tr>
</table>

<p class=MsoNormal style='margin-bottom:8.0pt;line-height:115%'><span
lang=EN-US style='line-height:115%;font-family:"Times New Roman",serif'>ER:
Estrogen Receptor, PR: Progesterone Receptor, HER2: Human Epidermal Growth
Factor Receptor 2, EIC: Extensive Intraductal Carcinoma, LVI: Lymphovascular
Invasion, PNI: Perineural Invasion, TMX: Tamoxifen, AI: Aromatase Inhibitor,
RT: Radiotherapy, CT: Chemotherapy, AC: Axillary Curettage, SLND: Sentinel
Lymph Node Dissection</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>&nbsp;</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure Legends</span></b></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure 1a. </span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Survival
curve DFS of Non-Special Type BC and Special Type BC subgroups using
Kaplan-Meier method</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure 1b. </span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Survival
curve of OS times of Non-Special Type BC and Special Type BC subgroups using
Kaplan-Meier method</span></p>

<p class=MsoNormal style='margin-bottom:8.0pt'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure 2a. </span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>Survival
curve of DFS times of Non-Special Type BC and Non-Lobular Special Type BC and
ILC subgroups using Kaplan-Meier method. <b><span style='background:yellow'>There
are 2066 patients at the beginning of the DFS curve, as 91 of a total of 2157
breast cancer patients had metastatic presentation at baseline.</span></b></span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure 2b.</span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>
Survival curve of OS times of Non-Special Type BC and Non-Lobular Special Type
BC and ILC subgroups using Kaplan-Meier method</span></p>

<p class=MsoNormal style='text-align:justify'><b><span lang=EN-US
style='line-height:200%;font-family:"Times New Roman",serif'>Figure 3.</span></b><span
lang=EN-US style='line-height:200%;font-family:"Times New Roman",serif'>� Subgroup
distribution according to histopathological subgroup differentiation, <b>3a</b>.
Non-Special Type BC, <b>3b</b>. Invasive Lobular Special Type BC, <b>3c</b>.
Non-Lobular Special Type BC</span></p>

</div>

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